Bromocyclopentane → 1-(Cyclopropylmethyl)-3-cyclopentyl-7-(2-oxopropyl)-xanthine

HRID 1109494Notes

Reaction equation

HRID 1109494 reaction equation
[CH:1]1([CH2:4][N:5]2[C:14](=[O:15])[C:13]3[N:12]([CH2:16][C:17](=[O:19])[CH3:18])[CH:11]=[N:10][C:9]=3[NH:8][C:6]2=[O:7])[CH2:3][CH2:2]1.[CH:20]1(Br)[CH2:24][CH2:23][CH2:22][CH2:21]1>>[CH:1]1([CH2:4][N:5]2[C:14](=[O:15])[C:13]3[N:12]([CH2:16][C:17](=[O:19])[CH3:18])[CH:11]=[N:10][C:9]=3[N:8]([CH:20]3[CH2:24][CH2:23][CH2:22][CH2:21]3)[C:6]2=[O:7])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 8728BromocyclopentaneHCID 190206611-Cyclopropylmethyl-7-(2-oxopropyl)xanthine

Product 1

HCID 190206601-(Cyclopropylmethyl)-3-cyclopentyl-7-(2-oxopropyl)-xanthine

Procedure

The title compound was prepared from 1-cyclopropylmethyl-7-(2-oxopropyl)xanthine and cyclopentylbromide in an analogous procedure to that of Example 19. The product was obtained as a crystalline solid; m.p. 155° C.

Workup

  1. customThe product was obtained as a crystalline solid

Sources & evidence

ORD record
ord-828334aca8b44633a42891e3732d91fb
Source dataset
uspto-grants-1994_06
Patent number
US05321029

Reaction notes

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