Potassium Hydroxide → HCID 19020643, compound

HRID 1109496Notes

Reaction equation

HRID 1109496 reaction equation
[CH:1]1([CH2:4][N:5]2[C:14](=[O:15])[C:13]3[N:12](CCC(=O)C)[CH:11]=[N:10][C:9]=3[N:8]([CH2:21][CH:22]3[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]3)[C:6]2=[O:7])[CH2:3][CH2:2]1.[OH-].[K+]>C(O)C>[CH:1]1([CH2:4][N:5]2[C:14](=[O:15])[C:13]3[NH:12][CH:11]=[N:10][C:9]=3[N:8]([CH2:21][CH:22]3[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]3)[C:6]2=[O:7])[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 19020657HCID 19020657, compound

Product 1

HCID 19020643HCID 19020643, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

This was prepared from the compound of Example 21, 900 mg, by treating with 200 mg potassium hydroxide in 10 ml of ethanol for 1 hour at room temperature. The title compound was isolated in an analogous manner to Example 18, m.p. 181° C.

Sources & evidence

ORD record
ord-52938dc98835420aac494c104b3ba8f5
Source dataset
uspto-grants-1994_06
Patent number
US05321029

Reaction notes

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