4-Bromobutyronitrile → HCID 22401918, compound

HRID 1109560Notes

Reaction equation

[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][NH:7][CH2:8][C:9]1[S:10][CH:11]=[CH:12][CH:13]=1.Br[CH2:15][CH2:16][CH2:17][C:18]#[N:19]>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][N:7]([CH2:15][CH2:16][CH2:17][C:18]#[N:19])[CH2:8][C:9]1[S:10][CH:11]=[CH:12][CH:13]=1

Participants

Reactant 2

HCID 214124-Bromobutyronitrile

HCID 2524531-(Thiophen-2-yl)-N-[(thiophen-2-yl)methyl]methanamine

Product 1

HCID 22401918HCID 22401918, compound

Procedure

In a manner analogous to Example 21 a, 4-[N, N-bis-(2-thienylmethyl )amino]butyronitrile was prepared by alkylation of bis-(2-thienylmethyl)amine using 4-bromobutyronitrile.

Sources & evidence

ORD record: ord-643329d6f70845a09644623b9829e608
Source dataset: uspto-grants-1994_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05321047

Reaction notes

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