1,3-Bis[4-(4-nitro-6-fluorophenoxy)-alpha, alpha-dimethylbenzyl]benzene → 1,3-Bis[4-(4-amino-6-fluorophenoxy)-alpha, alpha-dimethylbenzyl]benzene

Participants

Reaction Steps

Successively, to a reduction vessel equipped with a thermometer, reflux condenser and stirrer, 115 g (0.184 mol) of 1,3-bis[4-(4-nitro-6-fluorophenoxy)-α, α-dimethylbenzyl]benzene, 250 g of isopropyl alcohol and 4.8 g of 5%-Pd/c having a moisture content of 50% were charged and reacted at 70°~80° C. for 4 hours in a hydrogen atmosphere. After finishing the reaction, the catalyst was filtered off and the filtrate was concentrated under reduced pressure to obtain 84.2 g (81% yield) of 1,3-bis[4-(4-amino-6-fluorophenoxy)-α, α-dimethylbenzyl]benzene as a light yellow crystal having a melting point of 130.4~132.9.

Provenance & Evidence