Triphenylphosphine → HCID 19019367, compound

Participants

Reaction Steps

5.1 mL (0.1 mole) Bromine are added dropwise at ambient temperature, while stirring, to a solution of 26.5 g (0.1 mole) triphenylphosphine in 600 mL anhydrous toluene, a white crystalline precipitate thereby being formed. After further stirring for 20 minutes at ambient temperature, 48.17 g (0.1 mole) 1-benzyl-2-hydroxymethyl-5-octadecyloxy-4(1H)-pyridone are added thereto in portions. Thereafter, the reaction mixture is stirred for 2 hours at 70° C., cooled and the precipitated product is filtered off, washed with toluene, dried and recrystallized from propan-2-ol, pale beige crystals being obtained; m.p. 92°-95° C.

Provenance & Evidence