N-Hydroxyphthalimide → HCID 67823271, compound

Participants

Reaction Steps

A suspension of 0.74 g (0.003227 mol) of trans-N-BOC-2-ethyl-4-hydroxypiperidine (cf. Example 3b), 0.526 g (0.003227 mol) of N-hydroxyphthalimide and 0.846 g (0.003227 mol) of triphenylphosphine in 10 ml of benzene is reacted in accordance with the general procedure of Example 3a with a solution of 0.566 ml (0.003385 mol) of diethyl azodicarboxylate (93%) in 2 ml of benzene, to give the title compound as a colourless resin; Rf =0.60 (silica gel/ethyl acetate:hexane (2:1)).

Provenance & Evidence