HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 3-(6-Fluoroquinol-2-yl-trans-ethenyl)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Isophthalaldehyde | HCID 34777 | — |
| Reactant | 6-Fluoro-2-methylquinoline | HCID 70784 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 3-(6-Fluoroquinol-2-yl-trans-ethenyl)benzaldehyde | HCID 86747933 | 50.7% |
Reaction Steps
Using the procedure of Preparation I1, 5.04 g of 2-methyl-6-fluoroquinoline, 4.20 g of isophthaldehyde and 8.86 ml of acetic anhydride in 100 ml of xylene gave 4.40 g of the titled product as a pale yellow solid, m.p. 110°-111° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05322847 |
| Source dataset | uspto-grants-1994_06 |
| ORD ID | ord-738497aa53d248f584e17253f2da180e |
| Source note | uspto-grants-1994_06 |