Acetone → 4-(2-(2-ethyl-1H-benzo[d]imidazol-1-yl)-8-(1-isopropyl-3-methoxyazetidin-3-yl)-9-methyl-9H-purin-6-yl)morpholine

HRID 110991Notes

Reaction equation

HRID 110991 reaction equation
[CH2:1]([CH3:2])[c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:24]3[CH2:25][CH2:26][O:27][CH2:28][CH2:29]3)[c:11]3[n:12][c:13]([C:18]4([O:22][CH3:23])[CH2:19][NH:20][CH2:21]4)[n:14]([CH3:17])[c:15]3[n:16]1)[cH:30][cH:31][cH:32][cH:33]2.[CH3:34][C:35]([CH3:36])=[O:37].[CH3:38][OH:39]>>[CH2:1]([CH3:2])[c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:24]3[CH2:25][CH2:26][O:27][CH2:28][CH2:29]3)[c:11]3[n:12][c:13]([C:18]4([O:22][CH3:23])[CH2:19][N:20]([CH:35]([CH3:34])[CH3:36])[CH2:21]4)[n:14]([CH3:17])[c:15]3[n:16]1)[cH:30][cH:31][cH:32][cH:33]2

Participants

4

Reactant 3

HCID 180AcetoneHCID 887MethanolHCID 596058342-(2-Ethylbenzoimidazol-1-yl)-8-(3-methoxyazetidin-3-yl)-9-methyl-6-morpholin-4-yl-9H-purine

Product 1

HCID 596053024-(2-(2-ethyl-1H-benzo[d]imidazol-1-yl)-8-(1-isopropyl-3-methoxyazetidin-3-yl)-9-methyl-9H-purin-6-yl)morpholine

Sources & evidence

ORD record
ord-a00d45430689493aa62382e1675e540f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…