HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 54339148, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone | HCID 6775 | — |
| Reactant | 16-Methylprogesterone | HCID 134874 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 54339148 | HCID 54339148 | — |
Reaction Steps
A mixture of 16α-methylprogesterone (792 mg) , DDQ (575 mg) and benzene are heated at reflux for 28 hr, after 20 hr additional DDQ (70 mg) is added. After refluxing, the mixture is cooled to 20°-25°, filtered followed by basic workup (ether - potassium carbonate - magnesium sulfate) to give 16α-methylpregna-1,4-diene-3,20-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05322943 |
| Source dataset | uspto-grants-1994_06 |
| ORD ID | ord-02cd405092e2485fa75c517c27027ad8 |
| Source note | uspto-grants-1994_06 |