Phenol → Diglycidyl ether

Participants

Reaction Conditions

Reaction Steps

A phenol derivative (5.28 g) of the following formula: ##STR21## S-(+)-epichlorohydrin (11.55 g), potassium t-butoxide (3.00 g) and t-butyl alcohol (45 ml) are mixed, the mixture is stirred at 60° C. for 3 hours. The reaction mixture is distilled under reduced pressure to remove the solvent and the residue is extracted with chloroform. The extract is distilled under reduced pressure to remove the solvent. The residue is purified by silica gel chromatography to give R isomer of glycidyl ether (5.82 g) of the following formula: ##STR22##

Provenance & Evidence