Thionyl Chloride → 4-[(S)-2-propoxypropanoyloxy]benzoyl chloride

HRID 1109950Notes

Reaction equation

HRID 1109950 reaction equation
[CH2:1]([O:4][C@@H:5]([CH3:18])[C:6]([O:8][C:9]1[CH:17]=[CH:16][C:12]([C:13](O)=[O:14])=[CH:11][CH:10]=1)=[O:7])[CH2:2][CH3:3].S(Cl)([Cl:21])=O>N1C=CC=CC=1>[CH2:1]([O:4][C@@H:5]([CH3:18])[C:6]([O:8][C:9]1[CH:17]=[CH:16][C:12]([C:13]([Cl:21])=[O:14])=[CH:11][CH:10]=1)=[O:7])[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 147935344-[(S)-2-Propoxypropanoyloxy]benzoic acid

Product 1

HCID 144195134-[(S)-2-propoxypropanoyloxy]benzoyl chloride

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The resulting carboxylic acid (2.45 g) was reacted with 10 ml of thionyl chloride and 0.2 ml of pyridine to obtain 2.61 g of 4-[(S)-2-propoxypropanoyloxy]benzoyl chloride.

Sources & evidence

ORD record
ord-860a35cb668d469b9dea4ec700d4d017
Source dataset
uspto-grants-1994_06
Patent number
US05324451

Reaction notes

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