4-Formylbenzoic acid → 4-Formylbenzoyl chloride

Participants

Reaction Steps

To 7.50 g of terephthalaldehydic acid (4-formylheuzoic acid) were added 20 ml of thionyl chloride and 1 ml of pyridine, followed by heating under stirring. After the reaction mixture became clear, stirring was further continued at reflux for 4 hours, followed by allowing to cool. The excess thionyl chloride was removed by distillation under reduced pressure, toluene was added to the residue, and any insoluble matter was separated by filtration. The toluene was removed from the filtrate by distillation to obtain 7.91 g of 4-formylbenzoyl chloride.

Provenance & Evidence