HRID1109952

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID135

4-Hydroxybenzoic acid

C7H6O3

HCID301556

4'-Hydroxy-4-biphenylcarboxylic acid

C13H10O3

结构：CC[C@H](C)COC(=O)c1ccc(-c2ccc(O)cc2)cc1

HCID13907538

未命名化合物

PRODUCTS

生成物

结构：CCCO[C@@H](C)C(=O)Oc1ccc(C(=O)Oc2ccc(-c3ccc(C(=O)OC[C@@H](C)CC)cc3)cc2)cc1

HCID14645452

未命名化合物

HCID14793534

未命名化合物

PROCEDURE

实验过程

4-[(S)-2-Propoxypropanoyloxy]benzoic acid was synthesized in the same manner as in Example 1, except for replacing 4'-hydroxybiphenyl-4-carboxylic acid as used in Example 1 with p-hydroxybenzoic acid. The resulting compound was reacted with 4'-[(S)-2-methylbutoxycarbonyl]biphenyl-4-ol to obtain 4'[(S)-2-methylbutoxycarbonyl]biphenyl-4-yl 4-[(S)-2-propoxypropanoyloxy]benzoate.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-09e3a23979084db981066bc05f414468
来源数据集: uspto-grants-1994_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05324451
来源说明: uspto-grants-1994_06

反应 SMILES

OC1C=CC([C:8]2[CH:13]=[CH:12][C:11]([C:14]([OH:16])=[O:15])=[CH:10][CH:9]=2)=CC=1.[OH:17][C:18]1[CH:26]=[CH:25][C:21]([C:22]([OH:24])=[O:23])=[CH:20][CH:19]=1.[CH3:27][C@@H:28]([CH2:46][CH3:47])[CH2:29][O:30][C:31]([C:33]1[CH:38]=[CH:37][C:36]([C:39]2[CH:44]=[CH:43][C:42]([OH:45])=[CH:41][CH:40]=2)=[CH:35][CH:34]=1)=[O:32]>>[CH2:29]([O:30][C@@H:21]([CH3:25])[C:22]([O:24][C:8]1[CH:9]=[CH:10][C:11]([C:14]([OH:16])=[O:15])=[CH:12][CH:13]=1)=[O:23])[CH2:28][CH3:27].[CH2:14]([O:15][C@@H:11]([CH3:12])[C:14]([O:17][C:18]1[CH:19]=[CH:20][C:21]([C:22]([O:45][C:42]2[CH:41]=[CH:40][C:39]([C:36]3[CH:37]=[CH:38][C:33]([C:31]([O:30][CH2:29][C@@H:28]([CH3:27])[CH2:46][CH3:47])=[O:32])=[CH:34][CH:35]=3)=[CH:44][CH:43]=2)=[O:24])=[CH:25][CH:26]=1)=[O:16])[CH2:11][CH3:10]