反应详情

16 g of 6-chloro-2-methylpyrimidine-4-carbonyl chloride are added dropwise at 10°-15° C. to 150 ml of water. The mixture is then stirred for 1/2 h, the solid is filtered off with suction, and the filter residue is then washed well with water and dried in vacuo at 50° C. 11.5 g of 6-chloro-2-methylpyrimidine-4-carboxylic acid of melting point 132° C. (dec.) are obtained in this way.

1. filtrationthe solid is filtered off with suction
2. washthe filter residue is then washed well with water
3. customdried in vacuo at 50° C