HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-nitro-1-phenoxybenzene → 5-Chloro-2-phenoxyaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-nitro-1-phenoxybenzene | HCID 891181 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5-Chloro-2-phenoxyaniline | HCID 66738 | 105.5% |
Reaction Steps
The title compound of Example 8 (76 g, 0.3 mol) was hydogenated with RaNi in THF (2.4 L). The product was distilled to yield a yellow liquid (69.5 g, 100%), which had a boiling point of 145°-150° C./1.5 mmHg. This material was employed in Example 10 without further purication.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05324722 |
| Source dataset | uspto-grants-1994_06 |
| ORD ID | ord-35bbd76f074146b4b5f7674f2b00094a |
| Source note | uspto-grants-1994_06 |