反应详情

温度

80 °C

A 100-ml two-necked flask equipped with a stirrer and a dropping funnel was charged with 15.3 g (16.7 mmol) of ethanolamine and 5.0 g of ethanol. While heating and stirring the mixture at 80° C. in a nitrogen atmosphere, an ethanol solution of 5.00 g (16.7 mmol) of 1-tetradecyloxy-3-methyl-2-butene oxide was added dropwise over 3 hours. After heating and stirring the mixture further for 16 hours, the resultant reaction mixture was concentrated under reduced pressure, and the resultant residue was purified by column chromatography on silica gel, thereby obtaining 3.47 g (yield: 58%) of the title compound (IIc-4).

1. customA 100-ml two-necked flask equipped with a stirrer and a dropping funnel
2. temperatureWhile heating
3. temperatureAfter heating
4. stirringstirring the mixture further for 16 hours
5. customthe resultant reaction mixture
6. concentrationwas concentrated under reduced pressure
7. customthe resultant residue was purified by column chromatography on silica gel