Salicylic Acid → HCID 178419863, compound

Participants

Reaction Steps

10.7 g (=0.037 mole) of tedisamil were dissolved in 50 ml of diethyl ether. A solution of 5.12 g (=0.037 mole) of salicylic acid in 50 ml of diethyl ether was added to the solution. The reaction mixture was stirred for 30 minutes. The resulting precipitate was separated from the mother liquor by suction filtration, and dried in a vacuum drying oven at 60° C. 14.5 g of tedisamil salicylate were obtained. DSC gave a melting range of 140.9 to 142.2° C. The base:acid ratio determined by titration was 1:1.0. Thermogravimetric analysis showed a 0.1% weight loss on drying.

Provenance & Evidence