Benzoic acid, 3-isothiocyanato- → HCID 10413552, compound

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Reaction Steps

7-(m-Carboxyphenylthiocarbamoylamino)-4-chloro-3-(2-bromoethoxy)isocoumarin was prepared from the reaction of m-carboxyphenyl isothiocyanate with 7-amino-4-chloro-3-(2-bromoethoxy)isocoumarin, yield 64%, m.p. 157°-158° C.; mass spectrum m/e 361 (M+ -(COOH)PhNH+1). Anal. Calc.: C, 45.85; H, 2.84. Found: C, 45.73; H, 2.86. The bromoethoxy compound was then reacted with thiourea to give the product, yield 21%; mass spectrum (FAB+) m/e 493 (M+ -Br).

Provenance & Evidence