Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 3-Nitrophenol | HCID 11137 | — |
| Reactant | Magnesium | HCID 5462224 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 3-Nitrophenyl acetate | HCID 15207 | — |
Reaction Steps
Magnesium turnings (1.2 g) were added to a solution of m-nitrophenol (6.95 g), benzene (40 ml) and acetyl chloride (4 g) and the solution heated for 1 hour at 90° C. The reaction mixture was diluted with ether and decanted from unreacted magnesium. The ether layer was washed successively with water, dilute NaOH and water. The organic layer was dried (Na2SO4) and the solvent removed in vacuo to give m-nitrophenyl acetate. m.p. 55°-56° C. 1H n.m.r. δ2.4, s, 3H, H3C--CO--; 7.4-8.4, m, 4H, ArH. υmax 1770 cm-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05324750 |
|---|
| Source dataset | uspto-grants-1994_06 |
|---|
| ORD ID | ord-a54a321eaf9a4e88a8c07bfb4a7f7fb9 |
|---|
| Source note | uspto-grants-1994_06 |
|---|
