Carbamic acid, ethyl ester → Ethylene glycol bis(2-oxo-1, 3-oxazolidin-5-ylmethyl)ether

Participants

Reaction Steps

8.7 parts of ethylene glycol diglycidyl ether was reacted with 8.9 parts of ethyl carbamate in the presence of 0.3 parts of N, N-dimethylbenzylamine and 0.3 parts of dibutyltin dilaurate at 140° C. for 2 hours. The product was purified by silica gel chromatography (developing solvent, ethyl acetate: methanol=4:1). 11.7 parts (90% of theory) of ethylene glycol bis(2-oxo-1, 3-oxazolidin-5-ylmethyl)ether was obtained as white crystals melting at 90°-95° C.

Provenance & Evidence