関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Aniline | HCID 6115 | — |
| 反応物 | Diethyl 2-butyl-3-oxobutanedioate | HCID 251159 | — |
| 生成物 | Diethyl 2-butyl-3-(phenylamino)-2-butenedioate | HCID 67576867 | 45.2% |
反応手順
A mixture of 1 g of aniline and 2.65 g of the product of Step A and 150 mg of siliporite® NK10 was stirred for 3 days at 75° C. and the reaction mixture was cooled and chromatographed on silica eluant: hexane - ethyl acetate (9-1) to obtain 1.55 g of the expected product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05324839 |
|---|
| 出典データセット | uspto-grants-1994_06 |
|---|
| ORD ID | ord-c88e5a59c26a4df9b7400e8ffa2216a1 |
|---|
| 出典メモ | uspto-grants-1994_06 |
|---|
