HCID 67683131, compound → HCID 54144314, compound

HRID 1110154Notes

Reaction equation

HRID 1110154 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([CH2:20][N:21]([CH2:28][C:29]([O:31]CC)=[O:30])[CH2:22][C:23]([O:25]CC)=[O:24])[N:15]=3)[N:11]=[C:10]([C:34]3[CH:39]=[CH:38][CH:37]=[C:36]([CH2:40][N:41]([CH2:48][C:49]([O:51]CC)=[O:50])[CH2:42][C:43]([O:45]CC)=[O:44])[N:35]=3)[CH:9]=2)[CH:5]=[CH:6][CH:7]=1>[OH-].[K+].CCO>[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:9]=[C:10]([C:34]3[CH:39]=[CH:38][CH:37]=[C:36]([CH2:40][N:41]([CH2:42][C:43]([OH:45])=[O:44])[CH2:48][C:49]([OH:51])=[O:50])[N:35]=3)[N:11]=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([CH2:20][N:21]([CH2:22][C:23]([OH:25])=[O:24])[CH2:28][C:29]([OH:31])=[O:30])[N:15]=3)[CH:13]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 67683131HCID 67683131, compound

Product 1

HCID 54144314HCID 54144314, compound

Reagents, catalysts & solvents 1

HCID 21946426Potassium hydroxide ethanolSolvent

Procedure

The corresponding tetraester, 10c (0.10 g, 0.17 mmol) was dissolved in 5 ml 0.5M KOH-EtOH solution. After 2 hours stirring at room temperature, the ethanol was evaporated to dryness and water was added. The mixture was stirred at room temperature for 30 min whereafter the product was precipitated with 2M hydrochloric acid.

Workup

  1. customthe ethanol was evaporated to dryness and water
  2. additionwas added
  3. stirringThe mixture was stirred at room temperature for 30 min whereafter the product
  4. customwas precipitated with 2M hydrochloric acid

Sources & evidence

ORD record
ord-8bb6878a76a1467398ca1878ebbf5491
Source dataset
uspto-grants-1994_06
Patent number
US05324825

Reaction notes

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