Methanol → N-(2-methoxy-2-oxoethyl)-N-[3,5-bis(decyloxy)phenyl]glycine

HRID 1110233Notes

Reaction equation

HRID 1110233 reaction equation
[CH2:1]([O:11][C:12]1[CH:13]=[C:14]([N:29]2[CH2:34][C:33](=[O:35])[O:32][C:31](=[O:36])[CH2:30]2)[CH:15]=[C:16]([O:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[CH3:37][OH:38]>>[CH3:37][O:38][C:33](=[O:35])[CH2:34][N:29]([C:14]1[CH:15]=[C:16]([O:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:17]=[C:12]([O:11][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])[CH:13]=1)[CH2:30][C:31]([OH:36])=[O:32]

Participants

3

Reactant 2

HCID 887MethanolHCID 193890794-[3,5-Bis(decyloxy)phenyl]2,6-morpholinedione

Product 1

HCID 19388975N-(2-methoxy-2-oxoethyl)-N-[3,5-bis(decyloxy)phenyl]glycine

Procedure

A solution of 0.469 g of 4-[3,5-bis(decyloxy)phenyl]2,6-morpholinedione in 50 ml of methanol was warmed to 50° and then was left at room temperature for 17 hours. The solvent was removed at reduced pressure to give 0.44 g, mp 61°-62° of pure N-(2-methoxy-2-oxoethyl)-N-[3,5-bis(decyloxy)phenyl]glycine.

Workup

  1. customThe solvent was removed at reduced pressure

Sources & evidence

ORD record
ord-7f191f8b22d148e08e4b1a7888bc72c4
Source dataset
uspto-grants-1994_06
Patent number
US05324747

Reaction notes

Loading…