反应详情

24.1 g (0.277 mmol) of manganese dioxide are added with stirring and at room temperature to a solution of 2.5 g (13.9 mmol) of ethyl 4-(hydroxymethyl)benzoate in an n-hexane/carbon tetrachloride (50 ml : 30 ml) mixture. After half an hour of stirring, the reaction is complete. After filtration of the reaction medium and removal of the solvents under vacuum, 1.76 g of a yellow oil which gives a single spot in TLC are obtained. A crystallization in isopropyl ether yields a white solid.

1. filtrationAfter filtration of the reaction medium and removal of the solvents under vacuum, 1.76 g of a yellow oil which
2. customgives a single spot in TLC
3. customare obtained
4. customA crystallization in isopropyl ether
5. customyields a white solid