反应详情

As in Example 115, (E)-5,5-bis(4-chlorophenyl)-2,4-pentadienoic acid (4.79 g) and 4-nitrophenol (2.5 g) in dichloromethane (50 mL) was treated with 1,3-dicyclohexylcarbodiimide (3.1 g). The mixture was stirred at 0°-5° C. for 1 hour, then at room temperature for 1 hour. The usual work up furnished 6.9 g of (E)-5,5-bis(4-chlorophenyl)-2,4-pentadienoic acid 4-nitrophenyl ester as a pale yellow oil homogeneous by tlc. This material was used without further purification in subsequent reactions.

1. waitat room temperature for 1 hour