Pyridine, 3-(4-aminobutyl)- → HCID 14347339, compound

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Reaction Steps

As in Example 134, a solution of (E)-5,5-bis(3,4-dimethoxyphenyl)-2,4-pentadienoic acid 4-nitrophenyl ester (4.9 g) and 3-pyridinebutanamine (1.5 g) in tetrahydrofuran (25 mL) was stirred for 17 hours at room temperature and was then worked up in the usual manner. The crude amide was crystallized from ethyl acetate-hexane to provide 3.6 g of (E)-5,5-bis(3,4-dimethoxyphenyl)-N-[4-(3-pyridinyl)butyl]-2,4-pentadienamide mp 145°-146° C. Anal. Calculated for C30H34N2O5 : C, 71.69; H, 6.82; N, 5,57 Found: C, 71.33; H, 6.93; N, 5.72.

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