Sodium Hydroxide → HCID 14347263, compound

HRID 1110558Notes

Reaction equation

HRID 1110558 reaction equation
C[O:2][C:3](=[O:24])[CH:4]=[CH:5][CH:6]=[C:7]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[O:22][CH3:23])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[O:14][CH3:15].[OH-].[Na+]>CO>[CH3:23][O:22][C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=1[C:7]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[O:14][CH3:15])=[CH:6]/[CH:5]=[CH:4]/[C:3]([OH:24])=[O:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53786414HCID 53786414, compound

Product 1

HCID 14347263HCID 14347263, compoundYield 84.6%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In the manner described in Example 99, 5,5-bis(2-methoxyphenyl) -2,4-pentadienoic acid methyl ester (6.3 g) was saponified in a refluxing mixture of methanol (50 mL) and 1N NaOH (50 mL). After 45 minutes the crude acid was isolated in the normal manner and the crystallized from 2-propanol to yield 5.1 g of (E)-5,5-bis(2-methoxyphenyl)-2,4-pentadienoic acid, mp 196°-197° C.

Workup

  1. customAfter 45 minutes the crude acid was isolated in the normal manner
  2. customthe crystallized from 2-propanol

Sources & evidence

ORD record
ord-eb3e10dbe84245d0b38202bf2736c03c
Source dataset
uspto-grants-1990_12
Patent number
US04975438

Reaction notes

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