Sodium Hydroxide → HCID 14347283, compound

Participants

Reaction Steps

As described in Example 99, (E,E)-5-cyclohexyl-5-(4-methoxyphenyl)-2,4-pentadienoic acid methyl ester (5.9) was saponified in a refluxing mixture of methanol (20 mL) and 2N NaOH (20 mL). After 2 hours the reaction was worked up in the normal manner, and the crude was crystallized from cyclohexane-hexane to give 3.37 g of (E,E)-5-cyclohexyl-5-(4-methoxyphenyl)-2,4-pentadienoic acid, mp 130.5°-131.5° C.

Provenance & Evidence