Sodium Hydroxide → HCID 14347306, compound

Participants

Reaction Steps

As described in Example 99, (E,E)-5-(4-fluorophenyl)-2,4-decadienoic acid methyl ester (6.5 g) was saponified in a refluxing mixture of methanol (30 mL) and 2N NaOH (30 mL). After 2 hours the crude acid was isolated in the usual way and crystallized from hexane to yield 4.99 g of (E,E)-5-(4-fluorophenyl)-2,4-decadienoic acid, mp 116.5°-117.5° C.

Provenance & Evidence