Sodium Hydroxide → HCID 14347307, compound

Participants

Reaction Steps

As described in Example 99, (E,E)-5-(3,4-dimethoxyphenyl)-2,4-decadienoic acid methyl ester (4.9 g) was saponified in a refluxing mixture of methanol (30 mL) and 2N NaOH (30 mL). After 3 hours the reaction was worked up in the usual manner and the crude acid was crystallized from ether-hexane to provide 3.27 g of (E,E)-5-(3,4-dimethoxyphenyl)-2,4-decadienoic acid, mp 98°-99.5° C.

Provenance & Evidence