HRID1110694

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID192414

未命名化合物

结构：CC(C)[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)CNC(=O)[C@H](C)NC(=O)OC(C)(C)C)C(C)C)C(=O)NCC(=O)OCc1ccccc1

HCID131715251

未命名化合物

PRODUCTS

生成物

结构：CC(C)[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)CNC(=O)[C@H](C)NC(=O)OC(C)(C)C)C(C)C)C(=O)NCC(=O)O

HCID131715250

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID962

Water

H2O

PROCEDURE

实验过程

The nonapeptide benzylester (IX) was hydrogenated as described under VIII to obtain the acid in quantitative yield. Rf3 0 24. Anal. calcd. for C40H61N9O12 .H2O: C 55.09, H 7.16, N 14.3%. Found: C 54.69, H 7.16, N 13.81%.

WORKUP

后处理

customto obtain the acid in quantitative yield

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-11a1cca102d3474abec61f6d41418d27
来源数据集: uspto-grants-1990_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04976734
来源说明: uspto-grants-1990_12

反应 SMILES

[NH:1]([C:62]([O:64][C:65]([CH3:68])([CH3:67])[CH3:66])=[O:63])[C@H:2]([C:4]([NH:6][CH2:7][C:8]([NH:10][C@H:11]([C:15]([N:17]1[CH2:61][CH2:60][CH2:59][C@H:18]1[C:19]([NH:21][CH2:22][C:23]([NH:25][C@H:26]([C:34]([NH:36][CH2:37][C:38]([NH:40][C@H:41]([C:45]([NH:47][CH2:48][C:49]([O:51]CC1C=CC=CC=1)=[O:50])=[O:46])[CH:42]([CH3:44])[CH3:43])=[O:39])=[O:35])[CH2:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)=[O:24])=[O:20])=[O:16])[CH:12]([CH3:14])[CH3:13])=[O:9])=[O:5])[CH3:3].N(C(OC(C)(C)C)=O)[C@H](C(NCC(O)=O)=O)C>O>[NH:1]([C:62]([O:64][C:65]([CH3:68])([CH3:67])[CH3:66])=[O:63])[C@H:2]([C:4]([NH:6][CH2:7][C:8]([NH:10][C@H:11]([C:15]([N:17]1[CH2:61][CH2:60][CH2:59][C@H:18]1[C:19]([NH:21][CH2:22][C:23]([NH:25][C@H:26]([C:34]([NH:36][CH2:37][C:38]([NH:40][C@H:41]([C:45]([NH:47][CH2:48][C:49]([OH:51])=[O:50])=[O:46])[CH:42]([CH3:43])[CH3:44])=[O:39])=[O:35])[CH2:27][C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1)=[O:24])=[O:20])=[O:16])[CH:12]([CH3:13])[CH3:14])=[O:9])=[O:5])[CH3:3]