Sodium Hydroxide → HCID 15034333, compound

HRID 1110713Notes

Reaction equation

HRID 1110713 reaction equation
Cl.[CH2:2]([NH:9][CH2:10][CH2:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[OH-].[Na+]>ClCCl>[CH2:2]([NH:9][CH2:10][CH2:11][O:12][C:13]1[CH:14]=[CH:15][C:16]([OH:19])=[CH:17][CH:18]=1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22154105HCID 22154105, compound

Product 1

HCID 15034333HCID 15034333, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

N-Benzyl-2-(p-hydroxyphenoxy)ethylamine hydrochloride (3.5 g) was shaken with 1M sodium hydroxide solution (20 ml) and dichloromethane (20 ml). The organic layer was separated and washed with water (10 ml), dried (MgSO4) and the solvent evaporated to give N-benzyl-2-(p-hydroxyphenoxy)ethylamine as an oil.

Workup

  1. customThe organic layer was separated
  2. washwashed with water (10 ml)
  3. dry with materialdried (MgSO4)
  4. customthe solvent evaporated

Sources & evidence

ORD record
ord-5c6e5e735ef644a08a24f8db1861c7af
Source dataset
uspto-grants-1990_12
Patent number
US04977148

Reaction notes

Loading…