Potassium Nitrate → HCID 178481970, compound

HRID 1110740Notes

Reaction equation

HRID 1110740 reaction equation
[N+:1]([O-:4])([O-])=[O:2].[K+].[OH:6][C:7]1[C:16]([OH:17])=[N:15][C:14]2[C:9](=[CH:10][CH:11]=[C:12]3[N:20]([CH3:21])[N:19]=[N:18][C:13]3=2)[N:8]=1>S(=O)(=O)(O)O>[OH:6][C:7]1[C:16]([OH:17])=[N:15][C:14]2[C:9](=[CH:10][C:11]([N+:1]([O-:4])=[O:2])=[C:12]3[N:20]([CH3:21])[N:19]=[N:18][C:13]3=2)[N:8]=1

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 178481969HCID 178481969, compound

Product 1

HCID 178481970HCID 178481970, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

Finely powdered potassium nitrate (0.47 g, 4.6 mmol) was added portionwise to a stirred solution of 7,8-dihydroxy-3-methyl-3H-1,2,3-triazolo[4,5-f]quinoxaline (1.0 g, 4.6 mmol) in 20 ml of conc. sulfuric acid at 0° C. After 1 h the ice bath was removed and the mixture was stirred over night at room temperature. Then an additional amount of potassium nitrate (0.47 g) was added and stirring was continued over night at room temperature. The solution was poured into ice/water and the precipitated solid was collected, washed with water, and dried to give 1.0 g (83%) of the pure nitro compound; m.p.>300° C.; IR (KBr): 1710 cm-1 ; 1H-NMR (DMSO-d6): 4.50 (s, 3H, CH3), 8.18 (s, 1H, ArH), 12.13 (broad s, 1H, OH), 13.17 (broad s, 1H, OH).

Workup

  1. customAfter 1 h the ice bath was removed
  2. additionThen an additional amount of potassium nitrate (0.47 g) was added
  3. stirringstirring
  4. waitwas continued over night at room temperature
  5. additionThe solution was poured into ice/water
  6. customthe precipitated solid was collected
  7. washwashed with water
  8. customdried

Sources & evidence

ORD record
ord-980710b745e141888eba95edd37cb20d
Source dataset
uspto-grants-1990_12
Patent number
US04977155

Reaction notes

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