HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1110808Generated: November 2, 2026
Acetic Acid → 2-Methyl-1H-benzimidazole-5-carboxylic acid hydrochloride
https://huagongshe.com/reaction/1110808
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3,4-Diaminobenzoic acid | HCID 69263 | — |
| Product | 2-Methyl-1H-benzimidazole-5-carboxylic acid hydrochloride | HCID 17368245 | 94.5% |
Reaction Steps
After a mixture of 5.0 g (32.8 mmols) of 3,4-diaminobenzoic acid, 50 ml of conc. hydrochloric acid and 10 ml (0.175 mol) of acetic acid was heated at 100° C. for 24 hours, the solvent was distilled off under reduced pressure to give 6.6 g (94.5%) of 2-methylbenzimidazole-5-carboxylic acid hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04977175 |
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| Source dataset | uspto-grants-1990_12 |
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| ORD ID | ord-cdc6a915f22a4ff1a68d9a25a9f349e7 |
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| Source note | uspto-grants-1990_12 |
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