HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyclopentylmorpholine → Methyl 1-morpholino-2-oxa-3-aza-bicyclo[4.3.0]non-3-ene-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyclopentylmorpholine | HCID 13428024 | — |
| Reactant | Methyl 3-bromo-2-(hydroxyimino)propanoate | HCID 71339048 | — |
| Product | Methyl 1-morpholino-2-oxa-3-aza-bicyclo[4.3.0]non-3-ene-4-carboxylate | HCID 22154614 | 70.8% |
Reaction Steps
4.6 g (30 mmol) of morpholinocyclopentane are reacted with 1.75 g (10 mmol) of methyl 3-bromohydroxyiminopropionate by following the method of Example 1(a). 1.9 g of a colorless oil are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04977260 |
| Source dataset | uspto-grants-1990_12 |
| ORD ID | ord-0b7dab2a59ab449d8edb60cc1b90c458 |
| Source note | uspto-grants-1990_12 |