HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → Ethyl 2-(2,4-dichloro-5-fluoro-3-nitrobenzoyl)-3-ethoxyacrylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | Ethyl 2,4-dichloro-5-fluoro-3-nitro-beta-oxobenzenepropanoate | HCID 13733140 | — |
| Product | Ethyl 2-(2,4-dichloro-5-fluoro-3-nitrobenzoyl)-3-ethoxyacrylate | HCID 53944414 | — |
Reaction Steps
244.8 g of ethyl (2,4-dichloro-5-fluoro-3-nitro-benzoyl)-acetate are heated at 150°-160° C. with 166 g of triethyl orthoformate and 185 g of acetic anhydride for 3 hours. The mixture is then concentrated in vacuo and 270 g of ethyl benzoyl-ethoxy-acrylate are obtained as an oily residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04977263 |
| Source dataset | uspto-grants-1990_12 |
| ORD ID | ord-504182a38c5a42179db79dc68a882382 |
| Source note | uspto-grants-1990_12 |