Triethylamine → HCID 14478729, compound

Participants

Reaction Conditions

Reaction Steps

To the resultant compound from Example 9 (94.6 mg, 0.299 mmol) in methylene chloride (5 mL) at 0° C. was added 4-methylpentanoyl chloride (52ul, 0.37 mmol) and triethylamine (71 μl, 0.51 mmol). The mixture was stirred at 0° C. for 90 min, diluted with ethyl acetate, washed sequentially with 0.5M H3PO4 solution, 2M NaOH solution and brine, and then dried over Na2SO4 and evaporated to afford 0.118 g (95%) of the desired compound, m.p. 179°-183° C.

Provenance & Evidence