反应详情

To an 18.0 g (0.1 mole) amount of N-(aminothioxomethyl)benzamide in 300 ml of acetone was added 15.0 ml of methyl iodide (34.2 g, 0.24 mole). The mixture was heated as reflux and after about 5 minutes a solid precipitate formed. Refluxing was continued for 2 hours, then the hot reaction mixture was filtered to collect the precipitate. The precipitate was washed with two 50 ml portions of acetone, then air dried to give 28.9 g of the product as a white solid, mp 189°-190° C. (dec.).

1. temperatureThe mixture was heated
2. temperatureas reflux and after about 5 minutes a solid precipitate
3. customformed
4. temperatureRefluxing
5. filtrationthe hot reaction mixture was filtered
6. customto collect the precipitate
7. washThe precipitate was washed with two 50 ml portions of acetone
8. customair dried