5-Bromo-2-hydroxypyridine → HCID 14989563, compound

HRID 1111105Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[CH:4][C:5](=[O:8])[NH:6][CH:7]=1.[CH:9]([Si:12](OS(C(F)(F)F)(=O)=O)([CH:16]([CH3:18])[CH3:17])[CH:13]([CH3:15])[CH3:14])([CH3:11])[CH3:10]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:8][Si:12]([CH:16]([CH3:18])[CH3:17])([CH:13]([CH3:15])[CH3:14])[CH:9]([CH3:11])[CH3:10])=[N:6][CH:7]=1

Participants

Reactant 2

HCID 5995285-Bromo-2-hydroxypyridine

HCID 2724529Triisopropylsilyl trifluoromethanesulfonate

Product 1

HCID 14989563HCID 14989563, compound

Procedure

5-Bromo-2(1H)-pyridinone is allowed to react with triisopropylsilyl-trifluoromethanesulfonate to afford 5-bromo-2-(triisopropylsilyloxy)pyridine having the formula IV. ##STR15##

Sources & evidence

ORD record: ord-facc306f58864507ae2f71a8b619ad4d
Source dataset: uspto-grants-1990_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04978663

Reaction notes

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