HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 10104473, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 10352983 | HCID 10352983 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 10104473 | HCID 10104473 | 81.9% |
Reaction Steps
A mixture of 5-(1-hydroxycyclohexyl)-2-methoxypyridine (17.1 g), methyl iodide (11.7 g) and potassium carbonate (22.8 g) was heated in 330 mL of refluxing acetonitrile for 18 hours. The mixture was cooled and filtered, and the solids were washed with methanol. The filtrate was concentrated to yield 14.0 g of powder, which was used in subsequent reactions without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04978663 |
| Source dataset | uspto-grants-1990_12 |
| ORD ID | ord-b7355fc8543a49738b2422e68d186eaa |
| Source note | uspto-grants-1990_12 |