反应详情

To 5.63 gm (0.03 mole) of Girard's Reagent P in 50 ml of anhydrous methanol is added 3.63 gm (0.03 mole) of 3-acetylpyridine. The solution is refluxed 3 hr and cooled. The solvent is evaporated The residue is slurried in 100 ml of anhydrous ether and filtered. The crude product is recrystallized from absolute ethanol to afford 6.18 gm (71%) of the title compound; mp 237.2° (decomp).

1. temperatureThe solution is refluxed 3 hr
2. temperaturecooled
3. customThe solvent is evaporated The residue
4. filtrationfiltered
5. customThe crude product is recrystallized from absolute ethanol