HCID 3664836, compound → HCID 15079018, compound

HRID 1111128Notes

Reaction equation

HRID 1111128 reaction equation
CC(CC)[O-].[CH3:6][Si:7]([CH3:39])([CH3:38])[CH2:8][CH2:9][O:10][CH2:11][N:12]1[C:17](=[O:18])[C:16]([Cl:19])=[C:15]([NH:20][CH2:21][C:22]2[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[C:24]([O:30][CH2:31][CH3:32])[CH:23]=2)[C:14]([O:33][CH:34](CC)C)=[N:13]1.C[Si](C)(C)CCOCN1C(=O)C(Cl)=C(NCC2C=CC(OC)=C(OC)C=2)C(OC(CC)C)=N1>>[CH3:39][Si:7]([CH3:6])([CH3:38])[CH2:8][CH2:9][O:10][CH2:11][N:12]1[C:17](=[O:18])[C:16]([Cl:19])=[C:15]([NH:20][CH2:21][C:22]2[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[C:24]([O:30][CH2:31][CH3:32])[CH:23]=2)[C:14]([O:33][CH3:34])=[N:13]1

Participants

4

Reactant 3

HCID 3664836HCID 3664836, compoundHCID 15079019HCID 15079019, compoundHCID 15079020HCID 15079020, compound

Product 1

HCID 15079018HCID 15079018, compound

Procedure

In the same manner as above, by using sec-butoxide instead of sodium methoxide, 2-(2-trimethylsilylethoxymethy)-4-chloro-5-(3-ethoxy-4-methoxybenzylamino)-6-sec-butoxy-3(2H)pyridazinone (oily substance) and 2-(2-trimethylsilylethoxymethyl)-4-chloro-5-(3,4-dimethoxybenzylamino)-6-sec-butoxy-3(2H)pyridazinone (oily substance), were prepared from the corresponding 2-(2-trimethylsilylethoxymethyl)-4-chloro-5-(3-alkoxy-4-methoxybenzylamino)-6-nitro-3(2H)pyridazinones.

Sources & evidence

ORD record
ord-c5a692818f5a4f8cae094e871a18758e
Source dataset
uspto-grants-1990_12
Patent number
US04978665

Reaction notes

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