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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1111178Generated: October 29, 2026

alpha-Chloro-o-xylene → 4-Chloromethylbenzocyclobutene

https://huagongshe.com/reaction/1111178

Reaction equation

Participants

RoleNameHCIDCharge
Reactantalpha-Chloro-o-xyleneHCID 11093—
Reactant4-ChloromethylbenzocyclobuteneHCID 12617718—
Product4-ChloromethylbenzocyclobuteneHCID 12617718—
ProductHCID 131716734HCID 131716734—

Reaction Steps

Preparation of 4-chloromethylbenzocyclobutene was also effected by a similar procedure beginning with o-methylbenzyl chloride, however, the procedure yielded about a 1:2 mixture of 3-chloromethylbenzocyclobutene and 4-chloromethylbenzocyclobutene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04978721
Source datasetuspto-grants-1990_12
ORD IDord-72872c6d8d0b492aaabf85e6f60cec08
Source noteuspto-grants-1990_12