HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitrobenzaldehyde → MS-1845
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitrobenzaldehyde | HCID 7449 | — |
| Reactant | Nitrobenzylbromide | HCID 11356361 | — |
| Reactant | Phthalimide potassium salt | HCID 24194345 | — |
| Product | MS-1845 | HCID 309824 | — |
Reaction Steps
A process wherein from m-nitrobenzaldehyde is derived nitrobenzylbromide, which is then reacted with potassium phthalimide to obtain N-(m-nitrobenzyl)-phthalimide which is then subjected to a two-stage reduction to obtain m-aminobenzylamine (yield: Ca. 20%) (N. Kornblum et al., J.Am. Chem. Co., 71, 2137(1949)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04978792 |
| Source dataset | uspto-grants-1990_12 |
| ORD ID | ord-5b25770f424840f4a02a21ffd685408b |
| Source note | uspto-grants-1990_12 |