참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2,2-Dimethoxypropane | HCID 6495 | — |
| 반응물 | Tris(hydroxymethyl)nitromethane | HCID 31337 | — |
| 촉매 | Hydrochloric Acid | HCID 313 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | (2,2-Dimethyl-5-nitro-1,3-dioxan-5-yl)methanol | HCID 300859 | 82% |
반응 단계
To a 250 ml round bottom flask equipped with a stir bar was added 5 g (0.03 mol) tris(hydroxymethyl) nitromethane, 3.75 g (0.36 mol) 2,2-dimethoxypropane, 100 ml acetonitrile and 6 drops concentrated hydrochloric acid. The reaction was heated to 80° C. for 18 hours. After cooling to room temperature tte volatiles were removed in vacuo to give a white solid 2,2-dimethyl-5-hydroxy methyl-5-nitro-1,3-dioxane in 82% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04978793 |
|---|
| 출처 데이터셋 | uspto-grants-1990_12 |
|---|
| ORD ID | ord-4cb4e03e4c7a4972819b706c2c63d137 |
|---|
| 출처 메모 | uspto-grants-1990_12 |
|---|
