反应详情

0.8 g of ammonium chloride and 20 g of powdered zinc are added to 44 ml of aqueous-alcoholic solution (10% of water, 90% of alcohol). This mixture is brought to reflux with stirring, and 0.04 mole (8.5 g) of 4-nitro-N-[β-(methylthio)ethyl]aniline is added, the addition being regulated so as to maintain the reflux without heating. The decolorized reaction medium is filtered while boiling into a flask containing 8.5 ml of 36% strength hydrochloric acid. The expected product precipitates in the form of a dihydrochloride. It is dried under vacuum at 55° C.

1. temperatureto reflux
2. additionthe addition
3. temperatureto maintain the
4. temperaturereflux
5. temperaturewithout heating
6. customThe decolorized reaction medium
7. filtrationis filtered
8. customwhile boiling into a flask
9. additioncontaining 8.5 ml of 36% strength hydrochloric acid
10. customThe expected product precipitates in the form of a dihydrochloride
11. customIt is dried under vacuum at 55° C.