Ethanolamine → 4-[2-(2-Hydroxyethoxy)ethylamino]-3-nitrobenzonitrile

HRID 1111303Notes

Reaction equation

HRID 1111303 reaction equation

[OH:1][CH2:2][CH2:3][NH:4][C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][C:6]=1[N+:13]([O-:15])=[O:14].N[CH2:17][CH2:18][O:19]CCO.C(CN)O>>[OH:19][CH2:18][CH2:17][O:1][CH2:2][CH2:3][NH:4][C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][C:6]=1[N+:13]([O-:15])=[O:14]

Participants

4

Reactant 3

HCID 700Ethanolamine

HCID 13578Diglycolamine

HCID 15001944HC Yellow no. 14

Product 1

HCID 198289334-[2-(2-Hydroxyethoxy)ethylamino]-3-nitrobenzonitrile

Procedure

Preparation is similar to the synthesis in (a) above, except that 2-(2-aminoethoxy)ethanol is used in lieu of monoethanolamine.

Workup

customPreparation

Sources & evidence

ORD record: ord-4c4b34d234d04c7fa76c3946426d5efe
Source dataset: uspto-grants-1990_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04980158

Reaction notes

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