Ammonia → HCID 22152248, compound

HRID 1111355Notes

Reaction equation

HRID 1111355 reaction equation
[Cl:1][C:2]1[CH:33]=[CH:32][CH:31]=[CH:30][C:3]=1[C:4]([C:6]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:7]=1[S:13]([NH:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][C:27](Cl)=[O:28])(=[O:15])=[O:14])=[O:5].[NH3:34]>C1C=CC=CC=1>[Cl:1][C:2]1[CH:33]=[CH:32][CH:31]=[CH:30][C:3]=1[C:4]([C:6]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:7]=1[S:13]([NH:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][C:27]([NH2:34])=[O:28])(=[O:15])=[O:14])=[O:5]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 22152218HCID 22152218, compound

Product 1

HCID 22152248HCID 22152248, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A solution of 2 g of 11-[2-(2-chlorobenzoyl)-4-chlorobenzenesulphonamido]undecanoic acid chloride in 15 ml of anhydrous benzene is saturated with ammonia at 10° C. After stirring for two hours, the reaction medium is evaporated to dryness under vacuum, the residue is taken up with water and then extracted with ethyl acetate. After evaporation, the organic phase gives crystals which are recrystallized in benzene (1.22 g).

Workup

  1. customthe reaction medium is evaporated to dryness under vacuum
  2. extractionextracted with ethyl acetate
  3. customAfter evaporation
  4. customthe organic phase gives crystals which
  5. customare recrystallized in benzene (1.22 g)

Sources & evidence

ORD record
ord-b34ac2c595d1431b8ae9962e42f1417c
Source dataset
uspto-grants-1990_12
Patent number
US04980349

Reaction notes

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