Phosphorus pentachloride → HCID 15107290, compound

HRID 1111400Notes

Reaction equation

[CH2:1]([C:3]1[S:4][C:5]([C:10]([OH:12])=O)=[C:6]([CH2:8][CH3:9])[N:7]=1)[CH3:2].P(Cl)(Cl)(Cl)(Cl)[Cl:14]>>[CH2:1]([C:3]1[S:4][C:5]([C:10]([Cl:14])=[O:12])=[C:6]([CH2:8][CH3:9])[N:7]=1)[CH3:2]

Participants

Reactant 2

HCID 24819Phosphorus pentachloride

HCID 14653143HCID 14653143, compound

Product 1

HCID 15107290HCID 15107290, compound

Procedure

In accordance with the method of Synthesis Example 2, 2,4-diethylthiazole-5-carboxylic acid and phosphorus pentachloride were reacted to give 2,4-diethylthiazole-5-carboxylic acid chloride quantitatively. The 2,4-diethylthiazole-5-carboxylic acid chloride was used in the following reaction without purification.

Workup

customwere reacted

Sources & evidence

ORD record: ord-0b6d38a481cf47c19da3d54098705fba
Source dataset: uspto-grants-1990_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04980363

Reaction notes

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