Sodium Hydroxide → HCID 178509267, compound

HRID 1111436Notes

Reaction equation

HRID 1111436 reaction equation
[O:1]=[C:2]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:3][C:4]#[N:5].[N+]([O-])(O)=O.[NH2:16][NH:17][C:18](N)=N.[OH-].[Na+]>C(O)C>[NH2:5][C:4]1[C:3]([C:2]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=2)=[O:1])=[CH:18][NH:17][N:16]=1

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 64799BenzoylacetonitrileHCID 178513186HCID 178513186, compound

Product 1

HCID 178509267HCID 178509267, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A reaction mixture comprising 73.36 g of α-(dimethylamino)methylene]-β-oxo-2-benzenepropanenitrile, 63.45 g of aminoguanidine nitrate, 500 ml of ethanol and 36.6 ml of 10N sodium hydroxide was refluxed for 10 hours and then cooled. The resulting precipitate was collected and washed with water, giving 17.1 g of the desired product, mp 177°-179° C.

Workup

  1. temperaturecooled
  2. customThe resulting precipitate was collected
  3. washwashed with water

Sources & evidence

ORD record
ord-39639ba937d34e20ac2e18fc96b429ce
Source dataset
uspto-grants-1990_12
Patent number
US04980472

Reaction notes

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